Siddhartha Mukherjee, M.D.

Oncologist and Cancer Researcher | Pulitzer Prize-winning Science Writer
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Siddhartha Mukherjee, MD, DPhil, is a physician, scientist, author, and entrepreneur at the forefront of applying artificial intelligence to medicine. He is the Co-Founder and CEO (with Reid Hoffman and Ujjwal Singh) of ManasAI, a biotechnology company pioneering the use of advanced AI and machine-learning–driven platforms to dramatically accelerate the discovery and development of new medicines. At Manas AI, Dr. Mukherjee leads efforts to integrate large-scale biological data,computational models, and experimental science to transform how human therapeutics are designed and brought to patients.

Dr. Mukherjee is also an Associate Professor of Medicine at Columbia University Irving Medical Center (currently on leave). As a medical scholar, he has conducted research that has reshaped modern understanding of cancer biology and enabled the development of novel biological and cellular therapies. He was among the earliest leaders to apply AI-based algorithms to the discovery of human medicines and to translate these computational insights into clinical development. His work has led to a record number of concurrent clinical trials worldwide, spanning innovative treatments for ovarian, breast, and endometrial cancers, as well as leukemias and lymphomas. He is aco-inventor of several life-saving medicines, the founder of multiple biotechnology companies globally, and a member of the National Academy of Medicine.

In parallel with his scientific and entrepreneurial work, Dr. Mukherjee is an acclaimed author whose writing has shaped public understanding of medicine and science. The Emperor of All Maladies: A Biography of Cancer won the 2011 Pulitzer Prize for General Nonfiction, and The Gene: An Intimate History was a #1 NewYork Times bestseller and one of the most influential books of 2016, as recognized by The Washington Post and The New York Times. Both books were adapted into PBS documentary series by filmmaker Ken Burns, and The Emperor of All Maladies was named among Time magazine’s and The NewYork Times’ 100 best nonfiction books of the past century.

Dr. Mukherjee writes regularly for The New Yorker, The New York Times Magazine, and other leading publications, and has published original scientific research in journals including Nature, Cell, and The New England Journal of Medicine.

A native of India, Dr. Mukherjee earned his bachelor’s degree from Stanford University, was a Rhodes Scholar at Magdalen College, University of Oxford, and received his MD from Harvard Medical School. He completed his internal medicine residency at Massachusetts General Hospital and his hematology-oncology fellowship at the Dana-Farber Cancer Institute.

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Videos

On A.I., Longevity and Being a Digital Human
Siddhartha Mukherjee, M.D.
Would post-genomic knowledge change us as human beings?
Siddhartha Mukherjee, M.D.
Understanding The Gene | Live at Politics & Prose
Siddhartha Mukherjee, M.D.
The Gene — Live Talk | Vintage Books
Siddhartha Mukherjee, M.D.
The Gene, a PBS Ken Burns documentary | Preview
Siddhartha Mukherjee, M.D.
Soon we'll cure diseases with a cell, not a pill | TED 2015
Siddhartha Mukherjee, M.D.
Keeping health care workers, public safe amid coronavirus | MSNBC
Siddhartha Mukherjee, M.D.
Genetically Mapping the Future of Cancer | Talks at GS
Siddhartha Mukherjee, M.D.
Cancer: The Emperor of All Maladies | PBS Trailer
Siddhartha Mukherjee, M.D.

Articles

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Understanding Cancer
TIME 100 Health 2026
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The biographer of cancer writes a new chapter
The Observer
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Metabolism is the next frontier in cancer treatment
STAT
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The Catch in Catching Cancer Early
The New Yorker
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Covid's Deadliest Effect Took Five Years to Appear
New York Times
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Introducing Manas AI: Disrupting Drug Discovery
Manas AI
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On A.I., Longevity and Being a Digital Human
Ground Truths
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The Prize announces the 2023 longlist
The Baillie Gifford Prize
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What is a Cell?
C-Span
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What makes Siddhartha Mukherjee a literary phenomenon
The Week
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When our cells turn against us
The Harvard Gazette
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Why Aren't We All Bacteria?'
TIME

Podcasts

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